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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
9.09
Human Site:
S2090
Identified Species:
15.38
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S2090
T
R
S
P
P
R
P
S
P
G
G
L
H
Y
S
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S2045
T
R
S
P
P
R
P
S
P
G
G
L
H
Y
S
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
M1994
T
G
K
G
I
S
T
M
E
E
S
V
T
R
D
Dog
Lupus familis
XP_547004
2144
235913
P2021
K
N
G
T
R
S
P
P
R
P
S
P
G
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
R2070
N
G
T
R
S
P
P
R
P
S
P
G
G
L
H
Rat
Rattus norvegicus
XP_001073292
2181
239558
R2058
N
G
T
R
S
P
P
R
P
S
P
G
G
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
H2009
R
P
S
P
G
G
L
H
Y
S
D
E
D
I
C
Chicken
Gallus gallus
Q8AV58
2169
239459
S2042
T
R
S
P
P
R
P
S
P
G
G
L
H
Y
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
R2004
R
P
N
P
A
G
L
R
Y
S
D
E
D
I
C
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
F1155
L
V
L
L
I
L
C
F
I
K
R
S
K
G
G
Fruit Fly
Dros. melanogaster
O97394
2224
246236
P2101
G
V
H
L
G
K
S
P
P
R
P
S
P
A
S
Honey Bee
Apis mellifera
XP_623565
2176
242722
L2037
T
L
G
K
R
N
T
L
A
R
K
S
M
H
P
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
A2107
D
Q
S
R
E
P
P
A
Y
G
S
V
L
G
G
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
A2775
F
E
C
H
D
S
E
A
I
E
P
V
R
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
6.6
6.6
N.A.
13.3
13.3
N.A.
13.3
100
N.A.
6.6
0
13.3
6.6
20
0
P-Site Similarity:
100
100
13.3
6.6
N.A.
20
20
N.A.
13.3
100
N.A.
13.3
0
20
13.3
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
15
8
0
0
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
15
% C
% Asp:
8
0
0
0
8
0
0
0
0
0
15
0
15
0
8
% D
% Glu:
0
8
0
0
8
0
8
0
8
15
0
15
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
22
15
8
15
15
0
0
0
29
22
15
22
22
15
% G
% His:
0
0
8
8
0
0
0
8
0
0
0
0
22
8
15
% H
% Ile:
0
0
0
0
15
0
0
0
15
0
0
0
0
15
0
% I
% Lys:
8
0
8
8
0
8
0
0
0
8
8
0
8
0
0
% K
% Leu:
8
8
8
15
0
8
15
8
0
0
0
22
8
15
15
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
15
8
8
0
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
15
0
36
22
22
50
15
43
8
29
8
8
0
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
22
0
22
15
22
0
22
8
15
8
0
8
8
0
% R
% Ser:
0
0
36
0
15
22
8
22
0
29
22
22
0
0
29
% S
% Thr:
36
0
15
8
0
0
15
0
0
0
0
0
8
0
0
% T
% Val:
0
15
0
0
0
0
0
0
0
0
0
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
22
0
0
0
0
22
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _